Open AccessAntibacterial Activities and Phytochemical Screening of Crude Extracts of Calotropis gigantea (Giant Milk Weed)
Author(s) -
Oluwafemi Ojo JULIUS,
Veronica Oluwakemi OLUWASUSI,
M. F. Ibiyemi,
F. B. Oluwatobi
Publication year - 2021
Publication title -
south asian journal of research in microbiology
Language(s) - English
Resource type - Journals
ISSN - 2582-1989
DOI - 10.9734/sajrm/2021/v9i330210
Subject(s) - phytochemical , calotropis procera , gigantea , bacillus cereus , agar diffusion test , traditional medicine , biology , antimicrobial , antibacterial activity , proteus vulgaris , botany , chemistry , microbiology and biotechnology , bacteria , medicine , genetics
The root and leaf of were screened for its antimicrobial and phytochemical activities. The solvents used for the roots and leaves extraction were ethanol and water. The extracts were tested against infectious disease causing bacterial such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Klebsiellaaerogenesand α-haemolysin using the well diffusion method. The aqueous extracts of root of Calotropis gigantea against all the test bacteria ranged from 6.0 mm to 20.0 mm diameter zones of inhibition. The ethanolic extract of root of Calotropis gigantea inhibition against some the test microbe ranges from 6 mm to 14.0 mm diameter inhibitory zone. The ethanolic leaf extract of C. gigantea also showed an inhibition of 8mm to 20.0 mm. In present study, bacterial extract showed a varying zone of inhibition of the growth of tested organism than ethanol. Phytochemical properties of root and leaves of Calotropis gigantea obtain from ethanol and aqueous extracts were investigated. The results confirmed that presence of antibacterial activity and phytochemical in the shade dried extract of Calotropis gigantea against the human pathogenic organisms.