Open AccessExploring the Relationship between Bowel Microbiota and Impaired Glucose Tolerance
Author(s) -
Attia Ahmed Attia,
Alaa Elmetwalli,
Jayda G. Eldiasty
Publication year - 2022
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2022/v34i5b36054
Subject(s) - firmicutes , bacteroides , microbiome , biology , feces , proteobacteria , gut flora , human feces , bacteria , population , bacteroides fragilis , microbiology and biotechnology , bacteroidaceae , gut microbiome , food science , bioinformatics , genetics , medicine , 16s ribosomal rna , immunology , environmental health
Background and Aim: Because of the large number of genes found in the gut microbiome, it has recently been determined that numerous human microorganisms have significant implications for human health.
Aim: The significance of gut bacteria in the development of T2DM was investigated in this study.
Materials and Methods: Microbial species were extracted from fecal materials; they were identified and quantified using genomic spectrophotometric equipment, and certain biochemical parameters for Diabetes were quantified.
Result: We observed a concentration of firmicutes, Bacteroides, and proteobacteria, with the Escherichia coli population predominating. Biochemical parameters reveal a several-fold raised value for some biomarkers in T2DM. In a paired sample test results gave significant differences for all tested pairs.
Conclusion: Microbiomes can affect the gut environment and trigger alterations that embolden the development of T2DM, according to study findings.