Open AccessComparative Evaluation of Anaesthetic Efficacy of Ropivacaine and Articaine with Epinephrine for Buccal Infiltration Anaesthesia in Maxilla Central Incisor and their Effect on Cardiovascular Parameters – A Randomized Control Trial
Author(s) -
Vishwesh P. Joshi,
Manjusha Rawtiya,
Kailash Attur,
Nikunj Patel,
Pawan Gurjar,
Bhargav Chitroda
Publication year - 2022
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2022/v34i33b36137
Subject(s) - articaine , medicine , ropivacaine , anesthesia , general anaesthesia , lidocaine , blood pressure , maxillary central incisor , heart rate , pulpitis , dentistry , pulp (tooth)
Aim: To compare the effectiveness, latency time and onset of pulpal anaesthesia with 0.5% plain ropivacaine and 4% articaine with epinephrine 1:100 000 and to determine their probable effect on cardiovascular parameters.
Place and Duration of Study: Department of Conservative Dentistry and Endodontics, NPDCH, Visnagar, Gujarat between January 1st 2022 and January 31st 2022.
Methodology: 20 patients (10 male, 10 females) age range of 18-36 years were inserted 1.8 mL of the anaesthetic solution for buccal infiltration anaesthesia of maxillary central incisors deprived of caries, restorations or signs of pulpitis. The latency time, onset of pulpal anaesthesia and duration of pulp anaesthesia were assessed with an electric pulp tester. Heart rate and blood pressure were measured before, Immediate and after the onset of pulpal anaesthesia of the solutions. Data was sent for statistical analysis.
Results: The efficacy of anaesthesia of central incisors was 100% for both anaesthetics. The comparison of latency time and onset of pulpal anaesthesia were statistically significant for ropivacaine and articaine. Mean duration was less in Articaine group (206.50 ± 9.34) than Ropivacaine group (318.30 ± 43.21). Ropivacaine caused significant increases in blood pressure and heart rate.
Conclusion: Ropivacaine (0.5%) achieved effective and long duration of pulp anaesthesia. Ropivacaine could be beneficial for long lasting operative procedures without the need for a vasoconstrictor.