Open AccessNanomedicine in Treatment of Typhoid Fever: A Review
Author(s) -
Swati Pund,
Nitin Kharat,
Shaikh Sohel Shaikh Khalil,
Shoebuddin Zaheeroddin Shaikh,
Chetan Pulate,
Harshal Tare
Publication year - 2022
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2022/v34i24a35931
Subject(s) - typhoid fever , immunoassay , salmonella typhi , surface plasmon resonance , nanomedicine , medicine , nanotechnology , isolation (microbiology) , virology , immunology , biology , antibody , nanoparticle , materials science , bioinformatics , biochemistry , escherichia coli , gene
For effective management of typhoid, diagnosis of the disease must be done with speed and accuracy. Laboratory diagnosis of typhoid fever requires isolation and identification of Salmonella enterica serotype Typhi. In many areas where the disease is endemic, laboratory capability is limited. Recent advances in molecular immunology have led to the identification of sensitive and specific markers. Currently, alternative methods for biological molecular analysis are enzyme immunoassay, surface plasmon resonance and electrochemical immunoassay. With the development of nanotechnology, various nanoparticles and nano-quantum dots have been used as labels to enhance the sensitivity of the electrochemical immunoassay technique.