Open AccessOrganophosphorous Compounds in Assessment of Histomorphological Alterations of Natural Tooth
Author(s) -
Snega Thamilselvan,
Abirami Arthanari,
Abilasha Ramasubramanian,
Pratibha Ramani
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i63a35651
Subject(s) - distilled water , dentinal tubule , pesticide , carbofuran , dentin , dentistry , toxicology , chemistry , medicine , biology , ecology , chromatography
Background: Pesticide poisoning has indeed been recognized as a significant global health problem, and it is the most common cause of morbidity and mortality.Organophosphorus compounds (OP) are extensively used in agriculture, domestic pest control, and biological agents. Each year, an estimated 25 million farmers in developing countries are poisoned by pesticides, commonly OP, which is known to cause serious health ill effects.
Aim: The aim of this study is to assess the histomorphological alterations in natural tooth due to exposure to different organophosphorous compounds.
Materials and Methods: This research was carried out with organophosphorous compound - ANUFURAN 3G, carbofuran 3% CG purchased from local commercial market. The OP was available as solid crystals which made into a solution by adding 1g of OP compounds to 100ml of distilled water. The natural tooth was immersed in the respective solution for an hour and assessed for morphological &histological alterations through ground sections (200μm).
Results: Visually, there were very mild purplish tint on the cervical and apical 1/3rd of the tooth. Histologically, there were increased enamel lamellae which may have propagated to crack. The dentinal tubules were prominent and the pulpal tissue was completely dissolved.
Conclusion: The OP compounds did not prove to show any morphological or histological alterations to natural tooth.