Open AccessPost-COVID- 19 Mucormycosis: A Review
Author(s) -
Hemant A. Patil,
Mamidipalli Sai Spoorthy
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i61a35121
Subject(s) - mucormycosis , medicine , diabetes mellitus , incidence (geometry) , covid-19 , immunosuppression , intensive care medicine , dermatology , disease , surgery , infectious disease (medical specialty) , endocrinology , physics , optics
Background and Aims: After being affected by a severe second wave of COVID-19 with numerous cases and deaths, India is now facing new challenges due to the disease. One of these is the feared complication of rhino-orbital mucormycosis in post-infectious individuals. Case reports and research studies on this association are on the rise. Our goal is to conduct a comprehensive literature review to evaluate the distinctiveness of individuals with mucormycosis and COVID-19.
Methods: A literature search was done on the following databases: PubMed, Google Scholar, and Cochrane Library using the following keywords like COVID 19, Mucormycosis, Mucor, Novel coronavirus, and SARS CoV-2, a systematic.
Results: Studies have shown that history of diabetes mellitus and steroid treatments were the common possible factors for the increased post-covid-19 mucormycosis. Hyperglycemia secondary to uncontrolled hyperglycemic states like DM and immunosuppression secondary to covid-19 infection, steroid use form a vicious cycle causing mucormycosis.
Conclusion: Increased incidence of mucormycosis in India post-COVID infection appears to be due to a triad of diabetes, irrational steroid use, and COVID-19 itself. To decrease the frequency of deadly mucormycosis in patients with COVID-19, all attempts should be made to preserve optimal sugar levels in the body, and the use of corticosteroids should be restricted and should be given as per recommended by ICMR.