Evaluation of the Effectiveness of Titanium-prepared Platelet rich Fibrin (T-PRF) and Demineralized Freeze-dried Bone Allograft (DFDBA) in Socket Preservation Followed by Implant Placement Using Two Stage Approach

Background: The focus of the implant therapy is now shifting to a stable restoration rather than mere osseointegration. Placement of dental implants has become an indispensable part of mainstream dentistry, offering an improved quality of life to patients. One of the physiological changes that occurs after tooth extraction is alveolar ridge resorption. A variety of bone graft materials and platelet concentrates which are abundant in growth factors have been incorporated that provides the added effect of combination for early and better healing. Objectives: Evaluation of effectiveness of Titanium Prepared Platelet Rich Fibrin (T-PRF) and Demineralized Freeze-Dried Bone Graft (DFDBA) in socket preservation and simultaneous evaluation of implant stability three months after implant placement using two stage protocol. Methodology: Present study will be performed over one year period. Twelve patients, each having one tooth indicated for extraction in either of the arches will be selected. Atraumatic extraction will be done followed by socket preservation using combination of T-PRF and DFDBA to promote early healing followed by placement of implant. Expected Results: We expect early and better results of bone formation in healing sockets after preservation using T-PRF and DFDBA, which will be advantageous for implant placement. Better results in terms of bone volume, bone height, bone density and histomorphometry are expected. Conclusion: Combined effect of DFDBA and T-PRF is expected to improve the periodontal parameters including both soft tissue and hard tissue outcomes.