Open AccessEvaluation of Hypolipidemic Potential of Aqueous Seed Extract of Moringa oleifera –An In vitro Study
Author(s) -
Sariga Jayachandran,
S Kavitha,
R. Gayathri,
V. Vishnupriya,
Selvaraj Jayaraman
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i60b34934
Subject(s) - moringa , dpph , traditional medicine , antioxidant , aqueous extract , in vitro , food science , chemistry , medicinal plants , medicine , biochemistry
Various parts of the tree Moringa oleifera Lam belonging to the Moringceae family are used extensively by the Indians as a major food constituent and also as herbal medicine. The dried seeds are used as a hypolipidemic agent for patients who suffer from obesity.
Aim: The study was aimed at evaluation of hypolipidemic potential of aqueous seed extract of Moringa oleifera - an In vitro study.
Materials and Methods: Hypolipidemic potential and antioxidant potential of aqueous seed extract of Moringa oleifera was analysed and compared with the standard drug. The data were statistically analyzed by one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test and it was used to see the statistical significance among the groups. The results with the p<0.05 level were considered to be statistically significant.
Results: The DPPH radical scavenging activity showed that the plant extract possessed a significant In vitro antioxidant( Ic50=220µg/ml) and hypolipidemic activity.(( Ic50=380µg/ml).
Conclusion: The aqueous seed extract of Moringa oleifera exhibited a significant antioxidant and hypolipidemic potential.