Evaluation of Hypolipidemic Potential of Aqueous Seed Extract of Moringa oleifera –An In vitro Study

Various parts of the tree Moringa oleifera Lam belonging to the Moringceae family  are used extensively  by the Indians as a major food constituent and also as  herbal medicine. The dried seeds are used as a hypolipidemic agent for patients who suffer from obesity. Aim: The study was aimed at evaluation of hypolipidemic potential of aqueous seed extract of Moringa oleifera - an In vitro study.  Materials and Methods: Hypolipidemic potential and antioxidant potential of aqueous seed extract of Moringa oleifera was analysed and compared with the standard drug. The data were statistically analyzed by one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test and it was used to see the statistical significance among the groups. The results with the p<0.05 level were considered to be statistically significant. Results: The DPPH radical scavenging activity showed that the plant extract possessed a significant In vitro antioxidant( Ic50=220µg/ml)  and hypolipidemic activity.(( Ic50=380µg/ml). Conclusion: The aqueous seed extract of Moringa oleifera exhibited a significant antioxidant and hypolipidemic potential.