Isolation of Chemical Constituents and Invitro Antidiabetic Activity of Mirabilis Jalapa Flower Extracts | Zendy

Deepth D. Kodical | Zendy; J. Fernandes | Zendy; Jane Mathew | Zendy; K. Deepthi | Zendy; K. Vijay Bhaskar | Zendy

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Isolation of Chemical Constituents and Invitro Antidiabetic Activity of Mirabilis Jalapa Flower Extracts

Author(s) -

Deepth D. Kodical,

J. Fernandes,

Jane Mathew,

K. Deepthi,

K. Vijay Bhaskar

Publication year - 2021

Publication title -

journal of pharmaceutical research international

Language(s) - English

Resource type - Journals

ISSN - 2456-9119

DOI - 10.9734/jpri/2021/v33i60a34501

Subject(s) - phytochemical , lupeol , kaempferol , in vitro , chemistry , traditional medicine , flavonoid , terpenoid , chromatography , biochemistry , medicine , antioxidant

Objectives: The present work was designed to investigate the phytochemical and in vitro screening of the flower extracts of Mirabilis jalapa. Materials and Methods: Phytochemical constituents were isolated using column chromatography and characterized of the compounds were carried out using IR, 1H NMR, 13C NMR and mass spectroscopy data. In vitro anti-diabetic activity was evaluated by alpha-amylase inhibition assay and Alpha-glucosidase inhibition assay. Results: Phytochemical investigation of the ethanol extract revealed the presence of a flavonoid Kaempferol and a triterpenoid Lupeol. In vitro investigation indicated that the Mirabilis jalapa flowers extracts has considerable anti-diabetic activity Conclusion: The anti-diabetic activity may due to the presence of phytoconstituents like flavonoids, triterpenoids, steroids.

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