Open AccessAssociation of Sub-Clinical Hypothyroidism with Abnormal Levels of Lipid in the Population of Nawabshah, Pakistan
Author(s) -
Nasrullah Aamer,
Beenish Ghafar Memon,
Abdul Rashid,
Dayaram Makwana,
Samreen Memon,
Waseem Raja Memon
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i59a34291
Subject(s) - subclinical infection , dyslipidemia , medicine , thyroid stimulating hormone , triiodothyronine , endocrinology , hormone , thyroid , population , lipid profile , significant difference , cholesterol , obesity , environmental health
Aims: Aim of this investigation was to access the association of dyslipidemia with subclinical hypothyroidism.
Methodology: In this cross-sectional investigation, 1948 participants were recruited. Two groups were made; participants up to 18 years were in group A and Subjects over 18 years were incorporated in group 2. They were subdivided into control, subclinical hypothyroid 1, and subclinical hypothyroid 2. SPSS 21 was used for data analysis.
Results: Data of 1619 individuals were analyzed. The mean age of Group A participants was 12.79 ± 2.779, and the mean age of Group B participants was 42.58 ± 18.012. The prevalence of subclinical hypothyroid was found at 13.5 %. Significant differences have been observed while comparing Group A and Group B (P 0.05). No significant association between Controls and High-density Lipid values was found between Controls and subclinical hypothyroid.
Conclusion: We conclude that subclinical hypothyroidism leads to increased dyslipidemia. Lower Serum total cholesterol and low-density lipid levels were detected among children and participants under the age of 18 with Thyroid-stimulating hormone greater than 10 mIU/L. Thyroid-stimulating hormone less than 10.0 mIU/L had no lipid abnormalities in subclinical hypothyroid participants.