Open AccessPredictor of Severity of Lung Injury and Oxygen Saturation in COVID- 19 Patients
Author(s) -
Fahimeh Shahjooie,
Sadrollah Mahmudi,
Somayeh Mohammadi,
Hassan Goodarzi,
Mehrdad Farajy,
Mohammadreza Ghanee,
Akbar Ghorbani Alvanegh,
Amirhossein Ghazale
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i51a33474
Subject(s) - medicine , myalgia , oxygen saturation , comorbidity , covid-19 , chest pain , lung , severity of illness , disease , gastroenterology , oxygen , chemistry , organic chemistry , infectious disease (medical specialty)
Wide spectrum of clinical features of COVID-19 was seen from mild to severe. This is very important to determine the severity of disease, early management of severe disorder may increase the chance of survival.
Methods: This cross sectional study perform on 150 patients with mean age of 53 years that refer to from 21 February to 19 April 2020.
Result: The most comorbidity disease HTN, DM and IHD with prevalence of 26.2%, 20%, 11.3% which had higher severity of lung disease. There was a significant relationship between age, lymphopenia, CRP, IHD, DM, shortness of breath and body pain with the severity of lung injury, shortness of breath had higher severity of lung injury but myalgia had a lower severity rather than the others. level of the LDH was associated with chest CT scan score and so severe disease Further results showed that the mean±SD of LDH in 3 CT group were 576.30±214.82, 641.89± 277.07, 919.92± 382.14 in CT score less than 20, 20-50 and more than 50 respectively (P=0.002).
According this study there was significant relationship between age, BMI, CRP, shortness of breath and fever with blood oxygen saturation. Further results showed that the correlation between LDH and oxygen saturation was r=-0.31 (p=0.002)