Limiron Granules for Iron Deficiency Anemia in School going Children

Background: Iron Deficiency Anemia (IDA) is leading cause of the health derangements in school going children of India. Supplementation with iron preparation has been the integral part of our primary health policies still prevalence of childhood IDA is alarmingly high even though     nationwide national program and policies are implemented by GOI. Ayurveda traditional system of medicine defines the different herbo-mineral combination to treat IDA. Limiron Granules (LG) the proprietary Ayurveda medicine developed by SG Phyto Pharma Private Limited, Kolhapur Maharashtra India is used in this clinical trial for the management of childhood IDA. Aim: Clinical trial to evaluate the role of Limiron granule in children with IDA. Methods: Single arm Phase 3 clinical trial of this medicine has been carried out at Parul Ayurveda Hospital, Limda Vadodara, Gujarat, India. Total 104 children were enrolled in this study from rural and urban sector of Vadodara, Gujarat. Limiron granules were administered for 90 days and results were observed.  Observation and Results: Statistically significant (p < 0.01) results were obtain in subjective parameters of IDA like Pallor, fatigue, anorexia, stomatitis etc. while statistically significant result were observed in blood indices like MCH, MCH, MCHC with average increment of Hb 3 g/dL and increment in Sr. Iron level. Discussion and Conclusion: A Limiron granule is herbomineral combination containing iron in Fe2O3 form with Calcium in hydrate form, and natural phytosteroids. All these drugs help to promote the growth and improving the blood indices in children with IDA.