Open AccessNormal Reference Range for Serum TSH, Free T4, Total T4, and Total T3 on Roche® Platforms in Basrah, Iraq
Author(s) -
Nassar Taha Yaseen Alibrahim,
Samih A Odhaib,
Ali Hussain Ali Alhamza,
Ammar Mohammed Saeed Abdullah Almomin,
Ibrahim Abbood Zaboon,
Rudha Naser Hussein,
Muayad Kadhim,
Adel Gassab Mohammed,
Dheyaa Kadhim Al-Waeli,
Hussein Ali Nwayyir,
Haider Ayad Alidrisi,
Ibrahim Hani Hussein,
Mahmood Thamer Altemimi,
Husam Jihad Imran,
Abbas Ali Mansour
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i45a32727
Subject(s) - reference range , medicine , thyroid function , reference values , population , free thyroxine , thyroid , environmental health
Background: Thyroid function tests are mandatory in clinical practice because symptoms and signs are not reliable to discriminate between various types of thyroid disease.
Aim: The aim of this study was to determine assay-specific reference range for serum free T4, total T4, total T3 and TSH among healthy non-pregnant adult cohort for Roche® platforms in Basrah (Southern Iraq) from single laboratory in a tertiary center using indirect approach of the available data.
Methods: A Cross sectional study for non-pregnant adults 19 years and above. Sera were analyzed by using cobs e411 for thyroid functions tests.
Results: Total enrolled persons were 10,078. The 95% reference intervals for TSH were 0.20-6.50 μIU/mL, which increased with age though not linear, for free T4 were 0.8-1.70 ng/dL, for total T4 were 3.78-15.33 μg/dL, and for total T3 were 0.80-2.50 ng/mL.
Colcusion: Cobs e411(Roche® analytical platform) analyzer reference range for thyroid function cannot be applied for Iraqi population .