Open AccessTrends in Resistance to Cefazolin in a Military Hospital in Alkharj
Author(s) -
Nehad J. Ahmed
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i43a32505
Subject(s) - cefazolin , enterobacter cloacae , microbiology and biotechnology , medicine , drug resistance , antibiotic resistance , antibiotics , enterobacter , veterinary medicine , biology , escherichia coli , enterobacteriaceae , biochemistry , gene
Aim: This study aimed to describe the trends in resistance to cefazolin in a military hospital in Alkharj.
Methodology: This was a retrospective study that was conducted in Alkharj to describe the trends in resistance to cefazolin from 1st of January 2020 to 30th of June 2021. The results of bacterial cultures were collected from the microbiology laboratory in the hospital.
Results: The susceptibility rate of gram negative bacteria to cefazolin in 2020 was more than 50% except Enterobacter cloacae (susceptibility rate=0) and that the resistance of Escherichia coli to cefazolin was increased from 36% in 2020 to 48% in 2021. The present study showed that cefazolin should not use to treat infections caused by Enterobacter cloacae because of the high resistance rate (100%).
Conclusion: The present study showed that the bacterial resistance of several pathogens to cefazolin was high. It is important to monitor antimicrobial susceptibility continuously and to use antibiotics wisely to minimize emergence of drug resistant bacteria.