Open AccessMetabolomic Interactions: An Insight into Health and Disease
Author(s) -
Maheswara Reddy Mallu,
Shaik Mohammad Anjum,
Sai Sri Samyutha Katravulapalli,
Sri Sai Priya Avuthu,
Koteswara Reddy Gujjula,
Suryanarayana Veeravilli,
Anupama Ammulu Manne
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i39a32142
Subject(s) - metabolic engineering , metabolome , metabolomics , metabolic disease , metabolic pathway , computational biology , disease , metabolic network , biology , computer science , biochemical engineering , bioinformatics , medicine , engineering , metabolism , genetics , biochemistry , pathology , gene , endocrinology
Over the past decade, metabolic engineering has emerged as an active and distinct discipline characterized by its over-arching emphasis on integration. In practice, metabolic engineering is the directed improvement of cellular properties through the application of modern genetic methods. The concept of metabolic regulations deals with the varied and innumerable metabolic pathways that are present in the human body. A combination of such metabolic reactions paves the way to the proper functioning of different physiological and biological processes. Dealing with the adversities of a disease, engineering of novel metabolic pathways showcases the potential of metabolic engineering and its application in the therapeutic treatment of diseases. A proper and deeper understanding of the metabolic functions in the human body can be known from simulated yeast models. This review gives a brief understanding about the interactions between the molecular set of metabolome and its complexity.