Open AccessEvolving Trends and Changing Perspectives in ANCA Associated Vasculitis– A Review
Author(s) -
Monali Rajendrakumar Sahu,
Tanvi Wairagade,
Sonali Wairagade,
Ranjit Ambad,
Dhruba Hari Chandi
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i37b32041
Subject(s) - vasculitis , medicine , pathogenesis , immunology , inflammation , anca associated vasculitis , intensive care medicine , pathology , disease
Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a group of conditions characterized by inflammation and destruction affecting small to medium vessels accompanied by excess morbidity and mortality. These diseases present as multisystem diseases with variety of signs and symptoms. Earlier AAV were considered fatal diseases, however recent advances have changed them to chronic illnesses associated with morbidity& relapses. This review analyses recent developments in the pathogenesis, treatment and follow up of ANCA associated vasculitis.