Open AccessEffect of Triclosan and Sodium Monofluorophosphate on Plaque Reduction
Author(s) -
Seema Soomro,
Munir Ahmed Banglani,
Parveen Memon,
Mahwish Memon,
Abdul Qadir Dall,
Salman Shams
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i34a31835
Subject(s) - triclosan , toothpaste , dentifrice , dentistry , dental plaque , medicine , ingredient , chemistry , fluoride , inorganic chemistry , pathology
Objective: The aim of the study is to compare the clinical efficacy between two ingredient Triclosan and sodium monofluorophosphate on plaque accumulation.
Material and Methodology: This cross section study was carried out in school (Govt Girls High School Kotri). Total 100 school children were selected, between age ranges 13–16 years, which were divided in to two groups (group A & B) according to dentifrice given.
Group A: Toothpaste containing the active ingredient 0.3% Triclosan.
Group B: Toothpaste containing 0.8% sodium monofluorophosphate.
All patients were examined clinically for assessment using the Plaque index (PI) at follow up periods every week. Plaque was evaluated by using the silness-loe index. Oral examination for dental plaque assessment was carried out at the start of the study and the children were follow up to 10 weeks. Data were analyzed by SPSS 16 version and one-way ANOVA test.
Result: Triclosan toothpaste users experienced significant reduction in plaque accumulation as compared to the sodium monofluorophosphate toothpaste users.
Conclusion: At 3-weeks, Triclosan provided statistically signicantly greater reductions than sodium monofluorophosphate in plaque reduction.