Open AccessRecent Advances in Elastic Liposomes: Current Status and Future Perspective
Author(s) -
Ravika Nanda,
Raman Deep Singh Narang,
Kaur Anmoldeep,
. Mehak,
Karanbir,
Jasjeet Kaur Narang
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i31a31664
Subject(s) - transdermal , liposome , drug delivery , drug , nanotechnology , pharmacology , drug carrier , permeation , materials science , chemistry , biomedical engineering , medicine , membrane , biochemistry
Elastic liposomse (ELs) are the flexible liposomes formulated using phospholipids as well as edge activators. Edge activators provide elasticity to the Els. Els provide advantages over other formulations and have the ability to be delivered by different routes such as topical, transdermal, nasal, ocular, etc. Potential of encapsulating not only lipophillic but also hydrophillic drugs in a single vesicle, ability to pass through channels 1/10th of their diameter, increase in drug permeation, enhanced solubility of drug, patient compliance, prevention of degradation of drug makes them efficient carriers of drugs and leads to increased interest of researchers in them. This review provides understanding of composition of Els, advantages, method of preparation and the adaptable role played by ELs in the administration of numerous drugs for different diseases.