Open AccessIn-vitro Antibacterial Activity of Acacia Nilotica against Lactobacillus casei
Author(s) -
Abid Ali Khan,
Muhammad Owais Ismail,
Mirza Tasawer Baig,
Sadia Suri Kashif,
Aisha Jabeen,
Shumaila Sheikh,
Uzma Shahid
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i27a31489
Subject(s) - lactobacillus casei , antibacterial activity , traditional medicine , acacia , antimicrobial , medicinal plants , population , sodium hypochlorite , chemistry , biology , microbiology and biotechnology , medicine , food science , botany , bacteria , fermentation , environmental health , organic chemistry , genetics
Background: The role of Ethno-pharmacology is important to discover the new biologically active compounds. The process usually starts with searching of useful plants from different records to the development of methods for the industrial production of drugs. World Health Organization (WHO) states that more than 80% of population of the world makes the use of plants for the treatment of diseases. The extensive use of plants for therapeutic purposes has the history of centuries. Herbal pharmaceuticals have treated many diseases and confirmed the importance of medicinal plants on curative ground. The aim of this study was to evaluate in-vitro antibacterial activity of traditionally used Acacia nilotica by aqueous and Ethanolic extraction, against Lactobacilli casei.
Methodology: Disc diffusion method for antimicrobial susceptibility testing was carried out according to the Kirby-Bauer method to assess the presence of antibacterial activities of Ethanolic and Aqueous extracts of Acacia nilotica, against Lactobacillus casei. Results: It was found that Ethanolic extracts have antibacterial activity which was close to the positive controls (standards) of the study; 2.5% Sodium hypochlorite and 2% Chlorhexidine.
Conclusion: it was concluded that Ethanolic extract of Acacia nilotica, possesses antibacterial activity against Lactobacillus casei.