Open AccessImmunological Features and Hypotheses: Do SARS-CoV and MERS-CoV-Reported Individuals have Immunity against SARS-CoV-2 Infection
Author(s) -
Rafat Zrieq,
Najoua Haouas,
Reem Ali,
Hamoud F. Alshammari,
Fahad D. Algahtani
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2021/v33i26b31480
Subject(s) - virology , pandemic , immunity , context (archaeology) , covid-19 , biology , virus , immunology , coronavirus , medicine , immune system , infectious disease (medical specialty) , disease , paleontology , pathology
COVID-19 spreads abnormally compared to its counterparts in the same family "beta-coronaviruses". Today, we count more than 130 million affected humans affected by the COVID-19. Therefore, the study of means of prevention and treatment is an urgent need. Interestingly, the novel virus (SARS-CoV-2) has some similarities with SARS-CoV and MERS-CoV. It is known that heterologous immunity is well recognized within species of the same family. The use of previously recognized effective antibodies for SARS and MERS virus may prevent the COVID-19 pandemic. The objective of this study is to compare between SARS-CoV, MERS-CoV, and SARS-CoV-2 genomic and proteomic identity/similarity and their cross-immunity as well as their immunological features in the context of COVID-19 diseases prevention and treatment methods.