Immunological Features and Hypotheses: Do SARS-CoV and MERS-CoV-Reported Individuals have Immunity against SARS-CoV-2 Infection | Zendy

Rafat Zrieq | Zendy; Najoua Haouas | Zendy; Reem M. Ali | Zendy; Hamoud F. Alshammari | Zendy; Fahad D. Algahtani | Zendy

Open Access

Immunological Features and Hypotheses: Do SARS-CoV and MERS-CoV-Reported Individuals have Immunity against SARS-CoV-2 Infection

Author(s) -

Rafat Zrieq,

Najoua Haouas,

Reem M. Ali,

Hamoud F. Alshammari,

Fahad D. Algahtani

Publication year - 2021

Publication title -

journal of pharmaceutical research international

Language(s) - English

Resource type - Journals

ISSN - 2456-9119

DOI - 10.9734/jpri/2021/v33i26b31480

Subject(s) - virology , pandemic , immunity , context (archaeology) , covid-19 , biology , virus , immunology , coronavirus , medicine , immune system , outbreak , infectious disease (medical specialty) , disease , paleontology , pathology

COVID-19 spreads abnormally compared to its counterparts in the same family "beta-coronaviruses". Today, we count more than 130 million affected humans affected by the COVID-19. Therefore, the study of means of prevention and treatment is an urgent need. Interestingly, the novel virus (SARS-CoV-2) has some similarities with SARS-CoV and MERS-CoV. It is known that heterologous immunity is well recognized within species of the same family. The use of previously recognized effective antibodies for SARS and MERS virus may prevent the COVID-19 pandemic. The objective of this study is to compare between SARS-CoV, MERS-CoV, and SARS-CoV-2 genomic and proteomic identity/similarity and their cross-immunity as well as their immunological features in the context of COVID-19 diseases prevention and treatment methods.

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