Open AccessAlkanna tinctoria Derived Phytochemicals against Staphylococcus aureus Causing Eczema
Author(s) -
Utapa Nayak,
Elora Barik,
Bijan Kumar Patra,
Smruti Ranjan Behera,
Mukundjee Pandey,
Kalpita Bhatta,
Arsia Tabish,
Prabhashini Behera
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i930536
Subject(s) - staphylococcus aureus , naphthoquinone , chemistry , docking (animal) , enzyme , traditional medicine , biology , microbiology and biotechnology , biochemistry , botany , medicine , bacteria , genetics , nursing
Alkanna tinctoria plant extract is traditionally used to heal eczema. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 2-Hydroxy-3-Phenyl-1-4-naphthoquinone can can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.