Open AccessNigella sativa Derived Phytochemicals against Cough
Author(s) -
Diptiprajnya Sahoo,
Minati Nayak,
Sidhartha D. Ray,
Mukundjee Pandey,
Kalpita Bhatta,
Sushree Susmita Palei,
Debasmita Rautaray
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i930535
Subject(s) - nigella sativa , traditional medicine , cyclase , chemistry , biology , medicine , biochemistry , enzyme
Nigella sativa plant extract is traditionally used to cure cough. It is caused by Bordetella pertussis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the adenylate cyclase thereby interrupting the life cycle of the organism.