Open AccessCapsicum anum L. Derived Phytochemicals against Haemophilus influenzae Causing Bronchitis
Author(s) -
Debadatta Nayak,
Debesh Kumar Hota,
Tophani Sahu,
Soumya Jal,
Dipankar Bhattacharyay
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i730516
Subject(s) - haemophilus influenzae , chronic bronchitis , bronchitis , microbiology and biotechnology , haemophilus , chemistry , medicine , biology , bacteria , genetics , antibiotics
Phytochemicals from Capsicum anum L. plant extract are traditionally used to cure bronchitis. Bronchitis is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that myrcetin and quercetin can effectively deactivate the Palmitoyl-CoA hydrolase enzyme thereby interrupting the life cycle of Haemophilus influenza.