Open AccessCapsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus influenza causing Bronchitis
Author(s) -
Debesh Kumar Hota,
Debadatta Nayak,
Sitaram Swain,
Dipankar Bhattacharyay
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i630507
Subject(s) - haemophilus influenzae , apigenin , phytochemical , microbiology and biotechnology , bronchitis , biology , biochemistry , antibiotics , flavonoid , ecology , antioxidant
Phytochemicals from Capsicum plant extract are traditionally used to cure Bronchitis. It is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Apigenin can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.