Open AccessAntimicrobial Activity of Antibiotic Doped Carbon Nanoparticles Extracted from Kitchen Soot against Pathogenic Gram-negative Bacteria
Author(s) -
Habiba,
Israf Ud Din,
S. Tasleem,
Muhammad Mubashir,
Md. Afroz Bakht
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i3430958
Subject(s) - nanoparticle , carbon fibers , antibiotics , agar dilution , antibacterial activity , chemistry , soot , antimicrobial , nuclear chemistry , materials science , bacteria , nanotechnology , organic chemistry , minimum inhibitory concentration , biochemistry , biology , composite number , composite material , genetics , combustion
In this study carbon nanoparticles were extracted from kitchen soot and characterized by using UV/Visible spectroscopy. Amoxicyline and vibramycin were doped on the carbon nanoparticles by mixing the solutions of the aforementioned antibiotics and carbon nanoparticles and then evaporated to dryness at 50°C. The antibacterial potential of carbon nanoparticle, antibiotics and carbon nanoparticles doped antibiotics were evaluated using Agar tub dilution method against two bacterial strain i.e. P. Aerogunis and Salmonella entrica. The result indicated that the carbon nanoparticle doped antibiotics showed marked increase in the antibacterial potential with inhibition zone of 16.2 mm against P. aerogunisa and 12.5 mm against Salmonela entrica for Vibramycin Doped CNPs. The inhibition zone of Amoxicyline doped carbon nanoparticle is 25.0 mm against P. aerogunisa and 30.0 mm against Salmonela entrica.