Open AccessThe Relationship between Exercise and Medication in Preventing Severe forms of COVID-19 Infection
Author(s) -
Bogdan-Alexandru Hagiu
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i1430616
Subject(s) - biogenesis , mitochondrial biogenesis , ibuprofen , pathogenesis , mitochondrion , medicine , organelle biogenesis , pharmacology , covid-19 , trolox , chemistry , vitamin d and neurology , acetaminophen , disease , infectious disease (medical specialty) , biochemistry , oxidative stress , gene , antioxidant capacity
Prophylaxis of severe forms of COVID-19 infection can be achieved by exercising, especially endurance, which stimulates mitochondrial biogenesis and improves their functionality, these organelles having a key role in the pathogenesis of the disease. Some drugs and supplements that stimulate mitochondrial biogenesis through exercise (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox), ω3 fatty acids, vitamin C, zinc, vitamin B12, folic acid, magnesium, MitoQ) and others that inhibit it (acetylsalicylic acid, ibuprofen, acetaminophen).