Open AccessAnatomical Evaluation of Mandibular Bone Cortex in Patients with Mucopolysaccharidosis: A Case-Control Study
Author(s) -
Cledinaldo Lira,
Diego Henrique Pires Gonçalves,
Kamilly de Lourdes Ramalho Frazão,
Sandra Aparecida Marinho,
Sérgio Henrique Gonçalves De Carvalho,
Gustavo Pina Godoy,
Fátima Roneiva Alves Fonseca,
Dmitry José de Santana Sarmento
Publication year - 2021
Publication title -
journal of advances in medicine and medical research
Language(s) - English
Resource type - Journals
ISSN - 2456-8899
DOI - 10.9734/jammr/2021/v33i2131129
Subject(s) - medicine , mucopolysaccharidosis , gonial angle , mucopolysaccharidosis type i , panoramic radiograph , statistical significance , mann–whitney u test , radiography , dentistry , surgery , disease , enzyme replacement therapy
Aims: To evaluate the mandibular bone cortical of patients with mucopolysaccharidosis on panoramic radiograph, through radiomorfometric indices.
Study Design: Case-control study.
Place and Duration of Study: Sample: Department of Diagnostic Imaging of the Universidade Estadual da Paraíba, Campus VIII, in the city of Araruna, PB, between January and December of 2015.
Methodology: Panoramic radiographs of sixteen patients with mucopolysaccharidosis and 32 controls, organized by gender and age, composed the sample. The mandibular panoramic index, gonial index, antegonial index and mental index were evaluated. Pearson's Chi-square test, Fisher's exact test and Mann-Whitney test were used to statistical analysis with a level of significance of 5.0%.
Results: Mucopolysaccharidosis patients were mostly female (62.5%), with a mean age of 12.31 + 7.16 years, MPS VI (50.0%) being the most prevalent. Patients with mucopolysaccharidosis had higher values in the gonial (1.86+0.48), the antegonical (4.36+1.24) and the mental (5.24+1.21). However, only the antegoniac index presented a significant difference (P=0.047).
Conclusion: The antegoniac index was higher in patients with mucopolysaccharidosis and the other radiomorphometric measures were similar to those observed in the control group. Apparently, mucopolysaccharidosis is not related to decreased bone to mandibular quality.