Open AccessDiagnostic Value of Fetal Thymus Size in Intrauterine Growth Restriction
Author(s) -
Mohamed Mosaad Elshishiny,
Mohamed Mohsen Elnamoury,
Ayman Abd Elaziz Aldorf,
Essmat Hamdy AboZeid
Publication year - 2021
Publication title -
journal of advances in medicine and medical research
Language(s) - English
Resource type - Journals
ISSN - 2456-8899
DOI - 10.9734/jammr/2021/v33i1831052
Subject(s) - intrauterine growth restriction , umbilical artery , medicine , fetus , gestational age , obstetrics , pregnancy , diastole , gynecology , blood pressure , biology , genetics
Background: Changes in thymus size and histopathology have been observed both in animal models of intrauterine growth restriction (IUGR). The aim of the present study was to evaluate the size of the fetal thymus by sonography in pregnancies with IUGR and to search for a possible relationship between a fetal thymus size and adverse perinatal outcomes.
Methods: This prospective observational study was carried out on 100 participants who were divided into two groups. Group A: Study group which include 50 patients with IUGR. Group B: Control group which Include 50 normal patients with appropriate gestational age. All patients were subjected to: History taking: (Personal, Obstetric History, Maternal Medical History) and trans-abdominal ultrasound.
Results: IUGR group show statistically significant decrease in the estimate of fetal weight (EFW) compared to the control group (P 0.05).
Conclusions: IUGR is associated with small thymus and small fetal thymus may be an early indicator of adverse perinatal outcomes in pregnancies complicated by IUGR.