Open AccessEffect of Selenium-yeast on Cognitive Performance on Pregnant Dams Exposed to Noise Stress
Author(s) -
Okwute Michael Ochayi,
Ugochukwu Bond Anyaehie,
Eghosa Iyare,
Danazumi Umar Haruna,
Andrew Ivang
Publication year - 2022
Publication title -
annual research and review in biology
Language(s) - English
Resource type - Journals
ISSN - 2347-565X
DOI - 10.9734/arrb/2022/v37i130479
Subject(s) - selenium , alternation (linguistics) , spontaneous alternation , cognition , noise (video) , medicine , gestation , zoology , endocrinology , biology , chemistry , pregnancy , hippocampus , psychiatry , genetics , philosophy , linguistics , organic chemistry , artificial intelligence , computer science , image (mathematics)
A total of twelve pregnant Wistar rats were used, and randomly divided into three groups (n=4). Group A (negative control), not exposed to noise stress), group B (1mL/kg of distilled water + 4h /15 days noise stress), group C (0.04 mg/kg) of selenium-yeast + 4 h/15 days noise stress). On day 18 and 19 of gestation cognitive tests were conducted using Y-maze and Novel Object Recognition Test. A significant increase (P ˂ 0.05) was observed in the percentage alternation and discrimination index in group A compared with group B. However, the percentage alternation and DI were significantly (P ˂ 0.05) decreased in group C compared with group B. In conclusion, noise stress induces cognitive deficit, this deficit can be mitigated with the administration of selenium-yeast.