Open AccessWhy Recessive Lethal Alleles Have Not Disappeared?
Author(s) -
Jorma Jormakka,
Sourangshu Ghosh
Publication year - 2021
Publication title -
annual research and review in biology
Language(s) - English
Resource type - Journals
ISSN - 2347-565X
DOI - 10.9734/arrb/2021/v36i630391
Subject(s) - heterozygote advantage , allele , genetics , lethal allele , biology , gene , population , medicine , environmental health
The article derives the probability for lethal recessive alleles in the case of recessive disadvantage or advantage. It is shown that recessive advantage of a lethal gene can be detected by the ratio of heterozygotes and homozygotes. This demonstrates that higher IQ of certain ethnic groups cannot be explained by recessive advantage of lethal genes. The article shows that lethal genes can survive in the population if some lineages of families have much more children than the average.