Open AccessLong-Term Evolution of Patients with the Wolcott Rallison Syndrome: Case Series of 4 Patients and Review of Literatures
Author(s) -
Najlae El Hafidi,
Z. Imane
Publication year - 2021
Publication title -
asian journal of pediatric research
Language(s) - English
Resource type - Journals
ISSN - 2582-2950
DOI - 10.9734/ajpr/2021/v6i430202
Subject(s) - pediatrics , medicine , dysplasia , term (time) , diabetes mellitus , genetics , biology , endocrinology , physics , quantum mechanics
Wolcott-Rallison syndrome is a rare autosomal recessive disorder characterized by neonatal diabetes in consanguineous families. associated with liver dysfunction, epiphyseal dysplasia, and. growth retardation. It is caused by mutations in the gene encoding eukaryotic translation initiation factor 2α kinase 3 (EIF2AK3).
We report a long-term evolution of 4 patients with Wolcott Rallison syndrome.