Open AccessAn Overview on Biochemical Parameters and Organ Injury in COVID-19 Patients
Author(s) -
Sarita A. Shinde,
Vaishali V. Dhat,
Pradnya J. Phalak,
Umesh K. More,
Anita D. Deshmukh,
Mona Tilak
Publication year - 2022
Publication title -
asian journal of biochemistry, genetics and molecular biology
Language(s) - English
Resource type - Journals
ISSN - 2582-3698
DOI - 10.9734/ajbgmb/2022/v10i430252
Subject(s) - medicine , procalcitonin , organ dysfunction , hypoalbuminemia , acute kidney injury , creatinine , ferritin , liver injury , gastroenterology , prothrombin time , bilirubin , multiple organ dysfunction syndrome , pathology , sepsis
The Coronavirus disease (COVID-19) is considered as a respiratory disease which can cause a multi-organ injury like acute cardiac injury, kidney injury, and liver dysfunction. COVID-19 patients had The different of blood biochemical abnormalities where found in covid -19 patients which might indicate multiple organ dysfunction.
Hence the aim of the present study is provision of overview on organ injury and changes in biochemical parameters in Covid-19 patients.
The common laboratory abnormalities in COVID-19 patients included elevated inflammatory markers like CRP, ferritin, procalcitonin, cytokines and IL-6, IL-2, IL-7 and elevated prothrombin time and D-dimer. The cardiac injury is shown by increased concentration of CK-MB, LDH, and cTn and brain natriuretic peptide (BNP).
In liver and kidney dysfunction mild or moderate elevation of AST, ALT, total bilirubin, ALP, GGT, hypoalbuminemia, blood urea, creatinine and electrolyte disturbances were seen.
Hence reviewing currently available data, the present study can suggest that monitoring of the biochemical parameters may help in prediction of organ damage which further can prevent disease progression early interventions.