Open AccessPreimplantation Genetic Testing: A Review of Past and Current
Author(s) -
Aisha Elaimi
Publication year - 2021
Publication title -
asian journal of biochemistry, genetics and molecular biology
Language(s) - English
Resource type - Journals
ISSN - 2582-3698
DOI - 10.9734/ajbgmb/2021/v10i130230
Subject(s) - intracytoplasmic sperm injection , assisted reproductive technology , reproductive medicine , in vitro fertilisation , genetic engineering , genetic testing , infertility , preimplantation genetic diagnosis , reproductive technology , biology , engineering ethics , medicine , pregnancy , genetics , engineering , lactation , gene
The field of medical genetics has seen significant and incredible advances in technology for the past several decades. Genetic technologies, particularly in the reproductive medicine discipline, represent a fresh era in medicine that may develop significantly in the coming years. The purpose of Preimplantation Genetic Testing (PGT) in the situation of assisted reproductive technology (ART) treatments with IVF (in vitro fertilization) or ICSI (intracytoplasmic sperm injection) is particularly controversial as it is done before implantation [1]. However, despite the successful application of PGT in the field of IVF in overcoming infertility and genetic defects, the techniques pose various limitations, and concerns that need to be addressed to enhance their success rate [2]. This review will introduce PGT and summarize the molecular techniques used in its application as well as highlight the future advances in the field.