Open AccessPHARMACEUTICO-ANALYTICAL AND ANTIMICROBIAL STUDY OF JARIT VANGA BHASMA PREPARED WITH SPECIAL REFERENCE TO RASATARANGINI
Author(s) -
Raman Belge,
Rameshwar Pandey,
Prakash R. Itankar
Publication year - 2021
Publication title -
journal of pharmaceutical and scientific innovation
Language(s) - English
Resource type - Journals
ISSN - 2277-4572
DOI - 10.7897/2277-4572.103207
Subject(s) - antimicrobial , bacillus subtilis , candida albicans , klebsiella pneumonia , escherichia coli , staphylococcus aureus , chemistry , klebsiella pneumoniae , microbiology and biotechnology , food science , traditional medicine , biology , bacteria , biochemistry , medicine , genetics , gene
Background: Vanga Bhasma is said to possess antimicrobial activity (Jantughna Prabhava). Hence it was decided to evaluate the antimicrobial activity of Jarit Vanga Bhasma (JVB) prepared with special reference to Rasatarangini 18/29-33. Objectives: JVB was synthesized, analysed and its antimicrobial effects were studied in Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Escherichia coli and Candida albicans. Materials and Methods: The JVB was prepared and analyzed for the quality parameters mentioned in the Ayurvedic texts as well as the modern parameters like XRD, SEM and EDX to find out the nature of the Vanga Bhasma samples. The anti-microbial study was done to find out the anti-microbial efficacy of the JVB samples. Results and Conclusions: The adopted method for preparation of JVB was able to produce a Bhasma compatible to organoleptic parameters mentioned in the ancient texts. The obtained JVB was grayish white with the formation of the small sized particles as small as a nanoparticle which was confirmed by SEM study. XRD study confirms that Tin oxide is the major compound found in all the JVB samples. JVB showed antimicrobial activity in inhibiting the growth of Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Escherichia coli and Candida albicans with a concentration of 100mg/ml. The mean zone of inhibition was 12.33mm, 12.33mm, 14.66mm, 10.33mm and 16mm respectively. This outcome further supports the Krumighna and Jantughna properties (Anti-microbial activity) of Vanga Bhasma. Hence, JVB is said to possess Anti-Microbial activity.