Open AccessEPIDEMIOLOGICAL REVIEW OF MALARIA WITH REFERENCE TO CAUSALITY ANALYSIS, TREATMENT MONITORING AND OUTCOME
Author(s) -
K. Pratibha Ravindra,
Ratnendra Shinde,
Mayur Giri,
Ghotkar Pawan,
Gorte Mahend,
Kale Dnyanda,
Awale Pradip,
Sangle Dhananjay,
Amit S. Naik,
Kem Hos
Publication year - 2013
Publication title -
international journal of research in ayurveda and pharmacy
Language(s) - English
Resource type - Journals
eISSN - 2277-4343
pISSN - 2229-3566
DOI - 10.7897/2277-4343.04526
Subject(s) - causality (physics) , malaria , epidemiology , outcome (game theory) , medicine , intensive care medicine , environmental health , immunology , mathematics , physics , mathematical economics , quantum mechanics
Primary objective of the study was to assess causality analysis by patient profile, clinical and laboratory assessment. Secondary objective was to assess the Treatment patterns, clinical outcome, and outcome determinants leading to mortality. 150 Patients, diagnosed as malaria and admitted in medicine ward at Tertiary Care Center were enrolled over a period of 8 months after written informed consent. Their demographics as age, sex, and habitat and blood Investigations, especially parasite index (PI), gametocyte study, hemoglobin, platelet count were noted. Treatment of patients and their progress and outcome was noted .Descriptive statistics was used for analysis. Out of 150 patients 127 (85 %) were males and 23 (15 %) were females. Young age and lower socio-economic class was more affected. 88 % patients showed typical symptoms. Artesunate (88 %) was most commonly used followed by Chloroquine (12 %). Cure rate was 93 %. Majority (73 %) patients had parasitic index up to 3 %. 40 (26.68 %) patients showed parasitic index between 4 – 14 %. 93 Patients (62 %) had platelet count up to one lakh. P. Vivax infection (64 %) was most common followed by P. Falciparum (29 %) and mixed infection (7 %). Young age, lower income group, and mobility are risk factor for malaria. Low Hb, thrombocytopenia, high parasite index, old age, co morbid conditions are poor prognostic factors.Keywords