Open AccessEFFECT OF UNRIPE CARICA PAPAYA ON UTERUS
Author(s) -
Meera Sumanth,
K Ugendra
Publication year - 2013
Publication title -
international journal of research in ayurveda and pharmacy
Language(s) - English
Resource type - Journals
eISSN - 2277-4343
pISSN - 2229-3566
DOI - 10.7897/2277-4343.04308
Subject(s) - carica , uterus , traditional medicine , medicine , biology , horticulture
The present study was under taken to establish the uterine stimulant activity of aqueous extract of unripe Carica papaya. The effect of the aqueous extract of unripe Carica papaya was studied on isolated rat uterus and embryo. Uterine stimulant activity was compared with clinically available drug oxytocin and the effect on embryo was compared with misoprostol. In the in vitro model, Carica papaya showed contractile effect on the isolated uterus in diestrus stage and when administered orally in dose of 200 and 400 mg/kg to pregnant rats, resulted in gradual decrease in body weight indicating embryonic resorption. The present study confirms the uterine stimulant activity of aqueous extract of unripe Carica papaya fruit