Open AccessANTIHYPERLIPIDEMIC ACTIVITY OF SUAEDA MARITIMA (L.) DUMORTIER STEM IN TRITON INDUCED HYPERLIPIDEMIC RATS
Author(s) -
Sumitra Singh,
Rajinder Mann,
Surendra Sharma
Publication year - 2013
Publication title -
international journal of research in ayurveda and pharmacy
Language(s) - English
Resource type - Journals
eISSN - 2277-4343
pISSN - 2229-3566
DOI - 10.7897/2277-4343.04222
Subject(s) - chemistry , hyperlipidemia , biology , traditional medicine , medicine , endocrinology , diabetes mellitus
The present study was designed to investigate the hypolipidemic effect of Suaeda maritima (L.) Dumortier stem extracts in triton induced hyperlipidemia. Aqueous and alcoholic extracts of aerial parts of Suaeda maritima (L.) Dumortier were administered at dose 150 mg/kg and 300 mg/kg/day orally, respectively. Simultaneous administrations of stem extracts of Suaeda maritima (L.) Dumortier significantly prevent the rise in serum levels of total cholesterol (TC), triglyceride (TG), Low density lipoprotein (LDL) and very low density lipoprotein (VLDL) whereas significant increases in the level of high density lipoprotein (HDL) in both secretary and excretory phase. The Suaeda maritima (L.) Dumortier methanol extract of stem at dose 300mg/kg body weight orally showed significant antihyperlipidemic activity which may be due to the presence of triterpenoids and sterols found in the preliminary phytochemical screening