Open AccessSYNTHESIS, CHARACTERIZATION AND STUDY OF ANTIMICROBIAL ACTIVITY OF 2,6-DITERTIARY BUTYL-1,4-BENZOQUINONE HYDRAZONES
Author(s) -
Anees Pangal,
Khursheed Ahmed,
Sajid Shaikh
Publication year - 2013
Publication title -
international research journal of pharmacy
Language(s) - English
Resource type - Journals
ISSN - 2230-8407
DOI - 10.7897/2230-8407.04834
Subject(s) - antimicrobial , benzoquinone , chemistry , characterization (materials science) , organic chemistry , materials science , nanotechnology
Four 2,6-di-tert-butyl-1,4-benzoquinone hydrazones have been synthesized viz. A1, A2, A3 and A4. The purity was checked using HPLC. These compounds were characterized by FTIR and H1-NMR and they shows a prominent absorption of -(C=N-) in FTIR. It also shows a common peak of oleifinic proton at 6.50 Hz. These hydrazones were tested for their antimicrobial activity against Gram +ve and Gram –ve bacteria. A3 was found to be active at a minimum concentration of 50 μg•mL–1 where as A2 was inactive