Open AccessSPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF FORMOTEROL FUMARATE AND MOMETASONE FUROATE IN RESPICAPS
Author(s) -
Pallavi Raghunath Bhangale,
Harshita Jain
Publication year - 2013
Publication title -
international research journal of pharmacy
Language(s) - English
Resource type - Journals
ISSN - 2230-8407
DOI - 10.7897/2230-8407.04650
Subject(s) - mometasone furoate , chromatography , formoterol , medicine , chemistry , dermatology , pharmacology , corticosteroid , budesonide
The present work represents a UV-Spectrophotometric method for the simultaneous estimation of Formoterol Fumarate (FF) and Mometasone Furoate (MF) in respicaps dosage form. This method is based on area under curve (AUC) in the wavelength range of 210-220nm and 242-252nm. Linearity was found in the concentration ranges of 3-18μg/ml and 6-21μg/ml, for Formoterol Fumarate and Mometasone Furoate, respectively. This method was validated as per International Conference on Harmonization (ICH) guidelines. Validation results suggest that the proposed method is simple, rapid, accurate, sensitive and precise that can be applied for routine estimation of FF and MF in bulk drug and combined dosage form