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First‐Trimester Sonographic Findings Associated With a Dandy‐Walker Malformation and Inferior Vermian Hypoplasia
Author(s) -
Bornstein Eran,
Rodríguez José Luis Goncalves,
Pavón Erika Carolina Álvarez,
Quiroga Héctor,
Or Drorit,
Divon Michael Y.
Publication year - 2013
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/ultra.32.10.1863
Subject(s) - medicine , fourth ventricle , hypoplasia , cisterna magna , autopsy , agenesis , anatomy , cerebellar hypoplasia (non human) , occipital bone , cerebellum , magnetic resonance imaging , skull , pathology , radiology , cerebrospinal fluid , endocrinology
We report 2 cases in which first‐trimester measurements of the intracranial translucency and the brain stem‐to‐occipital bone diameter were markedly enlarged. This finding was thought to represent an abnormal fourth ventricle‐cisterna magna complex. Subsequently, the diagnoses of a Dandy‐Walker malformation with partial vermian agenesis in 1 case and inferior vermian hypoplasia in the other were established and confirmed by either postmortem autopsy or postnatal magnetic resonance imaging. These cases suggest that evaluation of the fourth ventricle‐cisterna magna complex, by measuring the intracranial translucency or brain stem‐to‐occipital bone diameter may identify some cases with structural malformations of the cerebellum as early as the first trimester.