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Sensitivity and Specificity of the Toe‐Brachial Index for Detecting Peripheral Arterial Disease
Author(s) -
Tehan Peta,
Bray Alan,
Keech Ruth,
Rounsley Richard,
Carruthers Angela,
Chuter Vivienne Helaine
Publication year - 2015
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/ultra.15.14.09071
Subject(s) - medicine , peripheral , receiver operating characteristic , arterial disease , ankle , population , positive predicative value , cardiology , vascular disease , surgery , predictive value , environmental health
Objectives The toe‐brachial index (TBI) is an alternative to the ankle‐brachial index (ABI) in screening for peripheral arterial disease (PAD); however, there is limited evidence comparing their diagnostic accuracy. This study compared the diagnostic accuracy of the ABI and TBI in a population at risk of PAD. Methods The sensitivity and specificity of the ABI and TBI were determined by color duplex sonography. Receiver operating characteristic (ROC) analysis was performed. Results A total of 119 participants were recruited (75 male and 44 female). The sensitivity for PAD was highest for the TBI (71%; ABI, 45%), and the specificity was highest for the ABI (93%; TBI, 78%). Receiver operating characteristic analysis indicated that the TBI (ROC area, 0.77; P = .0001) had greater clinical efficacy for diagnosis of PAD than the ABI (ROC area, 0.65; P = .005). Conclusions In specific populations, the TBI may have greater clinical efficacy than the ABI for diagnosis of PAD.