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Impaired Left Atrial Conduit Function in Coronary Artery Disease Patients With Poorly Controlled Diabetes: Two‐Dimensional Speckle‐Tracking Echocardiographic Study
Author(s) -
Hosseinsabet Ali,
MohseniBadalabadi Reza,
Moinfar Ali
Publication year - 2017
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/ultra.15.12065
Subject(s) - medicine , diabetes mellitus , cardiology , coronary artery disease , speckle tracking echocardiography , population , diastole , blood pressure , heart failure , endocrinology , ejection fraction , environmental health
Objectives The myocardium can be affected by diabetes mellitus. The effects of blood glucose control on some organs such as the kidney and eye have been previously reported. The aim of our study was to evaluate left atrial function via 2‐dimensional (2D) speckle‐tracking echocardiography in a group of coronary artery disease (CAD) patients with well‐controlled diabetes (hemoglobin A1c [HbA1c] < 7%) and to compare it with that in a group of CAD patients with poorly controlled diabetes. Methods This cross‐sectional study included 110 CAD patients, comprising 44 euglycemic control patients, 33 patients with well‐controlled diabetes (HbA1c < 7%), and 33 patients with poorly controlled diabetes. The study population thereafter underwent 2D speckle‐tracking echocardiography for an evaluation of their left atrial function. Results Our findings showed that the absolute values of early diastolic strain and early diastolic strain rate were lower in the CAD patients with poorly controlled diabetes than in the euglycemic control patients with CAD. Moreover, early diastolic strain in the CAD patients with poorly controlled diabetes was lower than that in the CAD patients with well‐controlled diabetes. Multivariable analysis revealed that poorly controlled diabetes was an independent determinant of early diastolic strain and strain rate. Conclusions The conduit function of the left atrium was impaired in the CAD patients with poorly controlled diabetes compared with that in the euglycemic control patients with CAD and the CAD patients with well‐controlled diabetes.