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Clinical Value of Integrated [ 18 F]Fluoro‐2‐Deoxy‐ d ‐Glucose Positron Emission Tomography/Computed Tomography in the Preoperative Assessment of Papillary Thyroid Carcinoma
Author(s) -
Choi Woo Hee,
Chung Yong-An,
Han Eun Ji,
Sohn Hyung Sun,
Lee Sang Hoon
Publication year - 2011
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.2011.30.9.1267
Subject(s) - medicine , positron emission tomography , thyroid carcinoma , nuclear medicine , positron emission tomography computed tomography , tomography , computed tomography , positron emission , radiology , thyroid cancer , carcinoma , positron , thyroid , pathology , nuclear physics , physics , electron
Objectives The purpose of this study was to evaluate the clinical value of preoperative [ 18 F]fluoro‐2‐deoxy‐ d ‐glucose (FDG) positron emission tomography/computed tomography (PET/CT) by comparing it to neck sonography in papillary thyroid carcinoma. Methods The diagnostic accuracies of PET/CT and sonography for detecting cervical node metastasis were compared. The association between FDG uptake in the primary tumor and the prognostic factors of differentiated thyroid cancer, such as tumor size, multiplicity, extrathyroid extension, and lymph node metastasis, was also assessed. Results Positron emission tomography/computed tomography showed lower sensitivity and higher specificity than sonography for detection of cervical node metastasis; however, no statistically significant difference was noted ( P > .99). Only the tumor size was associated with FDG uptake in the primary tumor. Conclusions [ 18 F]Fluoro‐2‐deoxy‐ d ‐glucose PET/CT could not provide additional information compared to neck sonography.