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Sepsis Rates After Ultrasound‐Guided Prostate Biopsy Using a Bowel Preparation Protocol in a Community Hospital
Author(s) -
Ruddick Francesca,
Sanders Paul,
Bicknell Simon G.,
Crofts Paul
Publication year - 2011
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.2011.30.2.213
Subject(s) - medicine , sepsis , bowel preparation , prostate biopsy , radiology , biopsy , prostate , protocol (science) , ultrasound , surgery , pathology , colonoscopy , colorectal cancer , cancer , alternative medicine
Objectives The purpose of this study was to determine whether the addition of disposable enemas and a 24‐hour diet of clear fluids to the bowel preparation protocol before transrectal ultrasound‐guided prostate biopsy decreases the rate of postbiopsy sepsis. Methods Sepsis rates of patients who underwent transrectal ultrasound‐guided prostate biopsies at a community hospital were analyzed before and after a new bowel preparation protocol was introduced in our department. All patients received the antibiotic ciprofloxacin both before and after the biopsy. The first group (190 patients) had a preparation protocol that only asked the patients to stop eating by midnight (clear fluids only) on the day before the biopsy. The second group involved 217 patients and followed a bowel‐cleansing biopsy preparation protocol. This protocol included the use of 2 disposable enemas and a diet of clear fluids for 24 hours preceding the biopsy. A systematic chart review was then performed to determine which patients had required treatment for postbiopsy sepsis. Results Sepsis occurred in 4 patients (2.11%) in group 1 and 1 patient (0.46%) in group 2. After performing a 2‐sided Fisher exact test, it was found that there was no significant difference between the groups at a 95% confidence level ( P = .189). Conclusions The 24‐hour clear‐fluid diet and the use of disposable enemas combined with a regimen of ciprofloxacin decreased the rate of postbiopsy sepsis in patients who underwent transrectal ultrasound‐guided prostate biopsy, but the results were not significantly different.

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