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Acoustic Radiation Force Impulse Elastography and Contrast‐Enhanced Sonography of Sinusoidal Obstructive Syndrome (Veno‐occlusive Disease)
Author(s) -
Fontanilla Teresa,
Hernando Concepción González,
Claros Juan Cristóbal Valenzuela,
Bautista Guiomar,
Minaya Javier,
del Carmen Vega Maria,
Piazza Ana,
Méndez Santiago,
Rodriguez Claudio,
Arangüena Rafael Pérez
Publication year - 2011
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.2011.30.11.1593
Subject(s) - medicine , elastography , acoustic radiation force , radiology , impulse (physics) , contrast (vision) , ultrasound , nuclear medicine , physics , quantum mechanics , artificial intelligence , computer science
We report quantitative liver acoustic radiation force impulse (ARFI) elastographic findings in 2 cases of sinusoidal obstructive syndrome and liver contrast‐enhanced sonographic features in one of these cases. To our knowledge, findings in this condition from these techniques have not been reported previously. Acoustic radiation force impulse elastography showed median high shear wave velocities (case 1, 2.75 m/s; case 2, 2.58 m/s) that normalized after specific treatment for sinusoidal obstructive syndrome; therefore, ARFI elastography provided quantitative information that helped diagnose this condition as well as monitor the response to treatment. Contrast‐enhanced sonographic findings in one of the cases showed patchy liver enhancement that correlated with the high‐velocity patchy distribution on ARFI elastography in that case and enhanced multidetector row computed tomographic findings in the other case. This contrast‐enhanced sonographic pattern progressively normalized during follow‐up after specific treatment. The elastographic features in both cases and contrast‐enhanced sonographic features in one of them contributed to early diagnosis and follow‐up of sinusoidal obstructive syndrome in both patients. Further prospective studies are necessary to define the role of ARFI elastography and contrast‐enhanced sonography in the early diagnosis and clinical follow‐up of this condition.