Premium
Sonographically Guided Transthoracic Biopsy of Peripheral Lung and Mediastinal Lesions
Author(s) -
Cao Bing-Sheng,
Wu Ji-Hua,
Li Xiao-Lin,
Deng Juan,
Liao Guo-Qing
Publication year - 2011
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.2011.30.11.1479
Subject(s) - medicine , echogenicity , biopsy , radiology , contrast (vision) , ultrasound , contrast enhanced ultrasound , lung , artificial intelligence , computer science
Objectives The purpose of this study was to assess the impact of contrast‐enhanced sonography on sonographically guided transthoracic needle biopsy of lung lesions. Methods A total of 121 patients underwent sonographically guided transthoracic needle cutting biopsy. Of the 121 patients, 62 (contrast‐enhanced sonography group) underwent contrast‐enhanced sonography before biopsy, and the information from contrast‐enhanced sonography was used to optimize the biopsy procedure. The remaining 59 patients constituted the non–contrast‐enhanced sonography group. The enhancement patterns and echogenicity were evaluated by the consensus of 2 sonographers. The diagnostic efficacy was compared between the contrast‐enhanced and non–contrast‐enhanced sonography groups. Results The enhancement intensity and extent varied greatly among different thoracic lesions, and an anechoic area (necrosis) was revealed in 26 of 62 lesions (41.9%) lesions after administration of the contrast agent. The overall diagnostic accuracy of sonographically guided transthoracic biopsy in this study was 85.9% (104 of 121). In the contrast‐enhanced sonography group, the initial biopsy led to correct diagnosis in 58 of 62 lesions (93.6%). In the non–contrast‐enhanced sonography group, the initial biopsy led to correct diagnosis in 46 of 59 lesions (78.0%). The difference in the diagnostic accuracy between the contrast‐enhanced and non–contrast‐enhanced sonography groups was statistically significant ( P < .05). Conclusions Contrast‐enhanced sonography enables differentiation of viable from necrotic portions of thoracic lesions and has a positive impact on the diagnostic efficacy of sonographically guided transthoracic needle biopsy.