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Pregnancy Outcome of Embryonic/Fetal Pleural Effusion in the First Trimester
Author(s) -
Hashimoto Kazumasa,
Shimizu Takashi,
Fukuda Misao,
Ozaki Mamoru,
Shimoya Koichiro,
Koyama Masayasu,
Murata Yuji
Publication year - 2003
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.2003.22.5.501
Subject(s) - medicine , pleural effusion , pregnancy , gestation , effusion , obstetrics , fetus , abortion , incidence (geometry) , pleural disease , gynecology , respiratory disease , surgery , lung , physics , optics , biology , genetics
Objective . To investigate the incidence of embryonic/fetal pleural effusion in the first trimester and its pregnancy outcome. Methods . A total of 965 viable singleton pregnancies confirmed by sonography between 7 and 10 weeks were examined to estimate the incidence of embryonic/fetal pleural effusion. When initial transvaginal sonography showed pleural effusion, serial ultrasound examinations were performed. Results . Pleural effusion was detected in 12 pregnancies (incidence, 1.2%; 95% confidence interval, 0.7–2.2), which involved bilateral thoracic cavities in all cases. The pregnancy outcome was assessed among 14 cases of pleural effusion, including 2 previously reported cases from the same institution. Among these, 12 pregnancies (86%) miscarried by 14 weeks' gestation. Karyotype was abnormal in 9 (82%) of 11 cases in which chromosomal analysis was successfully performed. Of these, 6 (67%) were 45,X. Conclusions . The results suggested that embryonic/fetal pleural effusion in early pregnancy was associated with poor pregnancy outcome such as spontaneous abortion and chromosomal abnormality.