Premium
Multiple Hypoechoic Hepatic Lesions in a Patient With Gaucher Disease
Author(s) -
Patlas Michael,
Hadas-Halpern Irith,
Reinus Constantin,
Zimran Ari,
Elstein Deborah
Publication year - 2002
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.2002.21.9.1053
Subject(s) - medicine , hepatosplenomegaly , malignancy , disease , hematologic malignancy , pathology , anemia , biopsy , gaucher's disease , lesion , cachexia , hematologic disease , cancer
The most common symptoms of Gaucher disease include hepatosplenomegaly and anemia and thrombocytopenia due to hypersplenism. We describe the case of a patient with Gaucher disease who had cachexia, massive hepatomegaly, and multiple focal hepatic lesions. The clinical and radiologic findings suggested malignancy. A biopsy specimen was taken from a hepatic lesion and revealed infiltration by Gaucher cells. We discuss our findings in light of the putative increased incidence of hematologic malignancies in patients with Gaucher disease.