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Nuchal translucency thickness and crown‐rump length in twin pregnancies with chromosomally abnormal fetuses.
Author(s) -
Pandya P P,
Hilbert F,
Snijders R J,
Nicolaides K H
Publication year - 1995
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.1995.14.8.565
Subject(s) - trisomy , crown rump length , fetus , medicine , aneuploidy , nuchal translucency , gestation , obstetrics , gynecology , pregnancy , anatomy , prenatal diagnosis , chromosome , biology , first trimester , genetics , gene
We retrospectively examined the crown‐rump length and nuchal translucency thickness of each fetus in eight twin pregnancies in which karyotyping at 10 to 14 weeks' gestation demonstrated that at least one of the fetuses was chromosomally abnormal. Eight fetuses had trisomy 21 and two had trisomy 18. The nuchal translucency thickness was more than 2.5 mm in nine (90%) of the trisomic fetuses and in one of the chromosomally normal ones. In contrast, the crown‐rump length was below the fifth percentile in only one of the fetuses with trisomy 18; all other measurements were within the normal range.