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Umbilical artery and ductal blood flow velocities in patients treated with aspirin and prednisone for presence of anticardiolipin antibody
Author(s) -
Forouzan I,
Cohen A W,
Lindenbaum C,
Samuels P
Publication year - 1993
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.1993.12.3.135
Subject(s) - medicine , umbilical artery , aspirin , ductus arteriosus , prednisone , cardiology , pregnancy , gestation , population , diastole , blood flow , obstetrics , blood pressure , genetics , environmental health , biology
Fifteen patients with previous pregnancy losses and positive plasma anticardiolipin antibody (ACA) were treated with prednisone (15 mg/day) and aspirin (80 mg/day). We measured Doppler velocimetries of umbilical artery and ductus arteriosus at intervals of 2 to 3 weeks starting from 20 weeks of gestation until delivery. Umbilical artery systolic/diastolic ratios (S/D) and maximum systolic velocities of ductus arteriosus did not differ from normal values. There were no poor outcomes in the treated group. ACA positive patients with previous poor pregnancy outcome when treated with prednisone and aspirin have umbilical artery and ductal flow velocities similar to those of the normal population.